Evaluation of Anti-Asthmatic Activity of Essential Oils from the Lauraceae Family in Lipopolysaccharide (LPS)-Stimulated NCI-H292 Cells

The Lauraceae family has commercial uses, such as in the food, pharmaceutical, and perfume industries. This study was conducted to investigate anti-asthmatic activity of essential oils from seven species family. were extracted leaves species, chemical composition investigated by gas chromatography-mass spectrometry. major constituents differed depending on even if they belonged same main camphor (89.09%) Cinnamomum camphora, linalool (26.91%) cassia, 1,8-cineole (23.90%) japonicum, d-limonene (10.27%) β-eudesmol (10.03%) Lindera obtusiloba, δ-cadinene (13.85%) α-phellandrene (11.57%) Machilus japonica, cis-,trans-β-ocimene (13.80% 12.06%) elemol (11.46%) Neolitsea aciculata, cis-β-ocimene (37.94%) sabinene (24.91%) sericea. using lipopolysaccharide-induced NCI-H292 cells. relative expression levels pro-inflammatory cytokines [interleukin (IL)-1β IL-6] mucus gene (MUC5AC MUC5B) significantly reduced Among oils, oil L. obtusiloba had most superior activity. These results suggest that could be used an agent suppress hypersecretion.